Article
Yeast histone H4 and H3 N-termini have different effects on the chromatin structure of the GAL1 promoter.
The EMBO journal - 3 Apr 1995
Fisher-Adams G, Grunstein M
Abstract excerpt
Deletion of the histone H4 N-terminal residues 4-23 decreases activation of the GAL1 promoter as much as 20-fold, while deletion of histone H3 N-terminal residues 4-15 hyperactivates GAL1 approximately 3-fold. In an attempt to understand the mechanisms by which these two different events take pla...
Topics
- Base Sequence
- Chromatin
- Fungal Proteins
- Genes, Fungal
- Genotype
- Histones
- Mediator Complex
- Methyltransferases
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Polymerase Chain Reaction
- Promoter Regions, Genetic
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Deletion
- Site-Specific DNA-Methyltransferase (Adenine-Specific)
- TATA Box
- Trans-Activators