Article
Transformation reversion induced in JB6 RT101 cells by AP-1 inhibitors.
Carcinogenesis - 1 Apr 1995
Dong Z, Lavrovsky V, Colburn N H
Abstract excerpt
The present study was directed to characterizing the reversion of neoplastic epidermal JB6 RT101 cells by AP-1 inhibiting drugs. Treatment of tumorigenic JB6 RT101 cells with retinoic acid (RA), fluocinolone acetonide (FA) or forskolin (FN) induced drug dependent (reversible) reversion of transformation. A synergistic effect on reversion was found with the three drugs in combination. Cells reverted by these three...
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