Article
Transformation reversion induced in JB6 RT101 cells by AP-1 inhibitors.
Carcinogenesis - 1 Apr 1995
Dong Z, Lavrovsky V, Colburn N H
Abstract excerpt
The present study was directed to characterizing the reversion of neoplastic epidermal JB6 RT101 cells by AP-1 inhibiting drugs. Treatment of tumorigenic JB6 RT101 cells with retinoic acid (RA), fluocinolone acetonide (FA) or forskolin (FN) induced drug dependent (reversible) reversion of transfo...
Topics
- Animals
- Anticarcinogenic Agents
- Cell Transformation, Neoplastic
- Cells, Cultured
- Colforsin
- Cyclic AMP
- Drug Resistance
- Fluocinolone Acetonide
- Glucocorticoids
- Mice
- Phenotype
- Sensitivity and Specificity
- Skin
- Skin Neoplasms
- Time Factors
- Transcription Factor AP-1
- Transcriptional Activation
- Tretinoin
