High-resolution genetic mapping of complex traits.

Article

High-resolution genetic mapping of complex traits.

American journal of human genetics - 1 May 1995

Kruglyak L, Lander E S

Abstract excerpt

Positional cloning requires high-resolution genetic mapping. To plan a positional cloning project, one needs to know how many informative meioses will be required to narrow the search for a disease gene to an acceptably small region. For a simple Mendelian trait studied with linkage analysis, the...

Topics

Alleles
Causality
Chromosome Mapping
Cloning, Molecular
Crossing Over, Genetic
Female
Humans
Lod Score
Male
Models, Genetic
Probability
Risk Factors

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