Article
PCR-detection of tumor-derived p53 DNA in cerebrospinal fluid.
American journal of clinical pathology - 1 Apr 1995
Rhodes C H, Honsinger C, Sorenson G D
Abstract excerpt
The sensitivity of polymerase chain reaction (PCR)-based methods for the detection of DNA offers opportunities for tumor diagnosis from the small amounts of tumor-derived DNA released into body fluids. Tumor-derived DNA can be distinguished from DNA derived from non-neoplastic cells by the presen...
Topics
- Adolescent
- Base Sequence
- Brain Neoplasms
- DNA, Neoplasm
- Exons
- Glioblastoma
- Humans
- Male
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Polymerase Chain Reaction
- Sensitivity and Specificity
