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Article

PCR-detection of tumor-derived p53 DNA in cerebrospinal fluid.

American journal of clinical pathology - 1 Apr 1995

Rhodes C H, Honsinger C, Sorenson G D

Abstract excerpt

The sensitivity of polymerase chain reaction (PCR)-based methods for the detection of DNA offers opportunities for tumor diagnosis from the small amounts of tumor-derived DNA released into body fluids. Tumor-derived DNA can be distinguished from DNA derived from non-neoplastic cells by the presence of tumor specific genomic alterations, such as mutations in the p53 gene. This case report describes the use of...

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Identifiers

PMID: 7726135
DOI: 10.1093/ajcp/103.4.404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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