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Article

Significance of P53 in human thyroid tumors.

World journal of surgery - 1 Jan 2000

Simon D, Goretzki P E, Gorelev V, Ebling B, Reishaus E, Lyons J, Haubruck H, Röher H D

Abstract excerpt

Mutational changes in the p53 tumor suppressor gene are the most frequent genetic alterations in human malignant tumors. Studies have shown a correlation of p53 expression in breast cancer with tumor prognosis. In contrast to mutational activation of ras and GSP in thyroid tumors, little is known...

Topics

Base Sequence
Cell Line
Genes, p53
Humans
Molecular Sequence Data
Mutation
Neoplasm Metastasis
Polymerase Chain Reaction
Prognosis
Thyroid Neoplasms

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7725741
DOI: 10.1007/BF00353758

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7725741-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Significance of P53 in human thyroid tumors.PMID 7725741Read ↗

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