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Article

Significance of P53 in human thyroid tumors.

World journal of surgery - 1 Jan 2000

Simon D, Goretzki P E, Gorelev V, Ebling B, Reishaus E, Lyons J, Haubruck H, Röher H D

Abstract excerpt

Mutational changes in the p53 tumor suppressor gene are the most frequent genetic alterations in human malignant tumors. Studies have shown a correlation of p53 expression in breast cancer with tumor prognosis. In contrast to mutational activation of ras and GSP in thyroid tumors, little is known about the role of p53 in thyroid tumor development. Therefore thyroid tumors and thyroid tumor cell lines were studied...

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Identifiers

PMID: 7725741
DOI: 10.1007/BF00353758

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Significance of P53 in human thyroid tumors.PMID 7725741Read ↗

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