Absence of p53 mutation in Japanese patients with malignant thyroid lymphoma.

doi:10.1007/BF03347774

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Article

Absence of p53 mutation in Japanese patients with malignant thyroid lymphoma.

Journal of endocrinological investigation - 1 Nov 1994

Iyota K, Takeda K, Matsuzuka F, Okabayashi T, Morita S, Kuma K, Hashimoto K

Abstract excerpt

Abnormalities of the gene encoding the sequence-specific DNA-binding protein, nuclear phosphorprotein p53, are among the most common genetic alterations observed in human cancers. A mutation of this tumor suppressor gene has been reported with a low prevalence in differentiated thyroid carcinomas...

Topics

Aged
Aged, 80 and over
Base Sequence
Exons
Genes, p53
Humans
Japan
Lymphoma
Middle Aged
Molecular Sequence Data
Mutation
Thyroid Neoplasms

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