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Article

Absence of p53 mutation in Japanese patients with malignant thyroid lymphoma.

Journal of endocrinological investigation - 1 Nov 1994

Iyota K, Takeda K, Matsuzuka F, Okabayashi T, Morita S, Kuma K, Hashimoto K

Abstract excerpt

Abnormalities of the gene encoding the sequence-specific DNA-binding protein, nuclear phosphorprotein p53, are among the most common genetic alterations observed in human cancers. A mutation of this tumor suppressor gene has been reported with a low prevalence in differentiated thyroid carcinomas, while the prevalence was high in undifferentiated thyroid carcinomas. We used denaturing gradient gel electrophoresis...

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PMID: 7699210
DOI: 10.1007/BF03347774

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Absence of p53 mutation in Japanese patients with malignant thyroid lymphoma.PMID 7699210Read ↗

Lack of mutation in exon 10 of p53 gene in thyroid tumors.Semantic proximity Read ↗

High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas.Semantic proximity Read ↗

Mutation of the p53 tumour suppressor gene and overexpression of its protein in 62 Japanese non-Hodgkin's lymphomas.Semantic proximity Read ↗

Low frequency of p53 gene mutations in breast cancers of Japanese-American women.Semantic proximity Read ↗

Detection of p53 mutations in B cell non-Hodgkin's lymphoma cell lines.Semantic proximity Read ↗

Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland.Semantic proximity Read ↗

High frequency of p53 gene mutations in primary breast cancers in Japanese women, a low-incidence population.Semantic proximity Read ↗

Significance of P53 in human thyroid tumors.Semantic proximity Read ↗

Low frequency of p53 mutations in human thyroid tumours; p53 and Ras mutation in two out of fifty-six thyroid tumours.Semantic proximity Read ↗

Molecular analysis of mutations in thyroid tumors with TGGE.Semantic proximity Read ↗

TP53 gene mutations in Hodgkin lymphoma are infrequent and not associated with absence of Epstein-Barr virus.Semantic proximity Read ↗

A mutated p53 gene alters thyroid cell differentiation.Semantic proximity Read ↗

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