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Article

A genetic locus on Plasmodium falciparum chromosome 12 linked to a defect in mosquito-infectivity and male gametogenesis.

Molecular and biochemical parasitology - 1 Jan 1995

Vaidya A B, Muratova O, Guinet F, Keister D, Wellems T E, Kaslow D C

Abstract excerpt

Infection of mosquitoes by Plasmodium spp. requires sexual differentiation of the malarial parasite in the vertebrate host and mating of the heterogametes in the vector midgut. A Plasmodium falciparum clone, Dd2, differentiates into normal-appearing gametocytes, yet poorly infects mosquitoes. The Dd2 clone, however, effectively cross-fertilized HB3, a Central American P. falciparum clone, and yielded several...

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Source

Identifiers

PMID: 7723789
DOI: 10.1016/0166-6851(94)00199-w

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