Article
A developmental defect in Plasmodium falciparum male gametogenesis.
The Journal of cell biology - 1 Oct 1996
Guinet F, Dvorak J A, Fujioka H, Keister D B, Muratova O, Kaslow D C, Aikawa M, Vaidya A B, Wellems T E
Abstract excerpt
Asexually replicating populations of Plasmodium parasites, including those from cloned lines, generate both male and female gametes to complete the malaria life cycle through the mosquito. The generation of these sexual forms begins with the induction of gametocytes from haploid asexual stage parasites in the blood of the vertebrate host. The molecular processes that govern the differentiation and development of...
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