Article
Proof of intragenic recombination in Plasmodium falciparum.
Molecular and biochemical parasitology - 1 Aug 1994
Kerr P J, Ranford-Cartwright L C, Walliker D
Abstract excerpt
Intragenic recombination in the merozoite surface protein MSP-1 of Plasmodium falciparum has been demonstrated in a cross between two cloned lines (3D7 and HB3) of this species. Following passage of a mixture of the clones through mosquitoes, uncloned progeny were examined by PCR for molecules containing sequences of both parent MSP-1 alleles. A recombinant molecule possessing both 3D7 and HB3 sequences has been...
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