Article
Proof of intragenic recombination in Plasmodium falciparum.
Molecular and biochemical parasitology - 1 Aug 1994
Kerr P J, Ranford-Cartwright L C, Walliker D
Abstract excerpt
Intragenic recombination in the merozoite surface protein MSP-1 of Plasmodium falciparum has been demonstrated in a cross between two cloned lines (3D7 and HB3) of this species. Following passage of a mixture of the clones through mosquitoes, uncloned progeny were examined by PCR for molecules containing sequences of both parent MSP-1 alleles. A recombinant molecule possessing both 3D7 and HB3 sequences has been...
Topics
- Alleles
- Animals
- Anopheles
- Antigens, Protozoan
- Base Sequence
- Crosses, Genetic
- DNA Primers
- DNA, Protozoan
- Female
- Male
- Meiosis
- Merozoite Surface Protein 1
