Article
Interchromosomal exchange of a large subtelomeric segment in a Plasmodium falciparum cross.
The EMBO journal - 1 Sept 1994
Hinterberg K, Mattei D, Wellems T E, Scherf A
Abstract excerpt
Duplications and interchromosomal transpositions of chromosome segments are implicated in the genetic variability of Plasmodium falciparum malaria parasites. One parasite clone, HB3, was shown to lack a subtelomeric region of chromosome 13 that normally carries a PfHRPIII gene. We show here that the chromosome 13 segment carrying PfHRPIII was replaced in HB3 by a duplicated terminal segment from chromosome 11....
Topics
- Alleles
- Aneuploidy
- Animals
- Antigens, Protozoan
- Antigens, Surface
- Base Sequence
- Chromosome Mapping
- Clone Cells
- Crosses, Genetic
- Genes, Protozoan
- Molecular Sequence Data
