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Article

Disruption of a <i>Plasmodium falciparum</i> gene linked to male sexual development causes early arrest in gametocytogenesis

7 Nov 2005

Abstract excerpt

A male gametocyte defect in the Plasmodium falciparum Dd2 parasite was previously discovered through the observation that all progeny clones in a Dd2 x HB3 genetic cross were the result of fertilization events between Dd2 female and HB3 male gametes. A determinant linked to the defect in Dd2 was subsequently mapped to an 800-kb segment on chromosome 12. Here, we report further mapping of the determinant to an...

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Identifiers

PMID: 16275909
DOI: 10.1073/pnas.0501858102

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