Mutational inactivation of the catalytic domain of guanylate cyclase-A receptor.

doi:10.1161/01.hyp.25.4.694

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Article

Mutational inactivation of the catalytic domain of guanylate cyclase-A receptor.

Hypertension (Dallas, Tex. : 1979) - 1 Apr 1995

Miao Z H, Song D L, Douglas J G, Chang C H

Abstract excerpt

Guanylate cyclase-A, the receptor for atrial natriuretic factor, contains a protein kinase-like domain and a catalytic domain in the intracellular region. To investigate the active site (the catalytic cavity) of guanylate cyclase-A, we amplified the catalytic domain plus three amino acids from th...

Topics

Adenylyl Cyclases
Amino Acid Sequence
Base Sequence
Catalysis
Conserved Sequence
Guanosine Triphosphate
Guanylate Cyclase
Molecular Sequence Data
Molecular Weight
Mutation
Oligonucleotide Probes
Receptors, Atrial Natriuretic Factor
Sepharose

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