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Article

Identification of the G protein-activating sequence of the single-transmembrane natriuretic peptide receptor C (NPR-C).

American journal of physiology. Cell physiology - 1 May 2003

Zhou Huiping, Murthy Karnam S

Abstract excerpt

Rat natriuretic peptide clearance receptor (NPR-C) contains four sequences capable of inhibiting adenylyl cyclase. We have undertaken mutational and deletion studies on the intracellular domain of rat NPR-C to determine which of these sequences is functionally relevant. Nine mutant receptors were constructed by deletion of 11 or 28 COOH-terminal residues or by site-directed mutagenesis of basic residues in a...

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Identifiers

PMID: 12676657
DOI: 10.1152/ajpcell.00520.2002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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