Identification of sequences mediating guanylyl cyclase dimerization.

doi:10.1021/bi00014a025

Back to search

Article

Identification of sequences mediating guanylyl cyclase dimerization.

Biochemistry - 11 Apr 1995

Wilson E M, Chinkers M

Abstract excerpt

Deletion mutagenesis was used to identify sequences required for dimerization and enzymatic activity of the intracellular domain of the membrane guanylyl cyclase, GC-A. The intracellular domain of GC-A contains a protein kinase-like domain near its amino terminus, a guanylyl cyclase catalytic dom...

Topics

Amino Acid Sequence
Base Sequence
Biopolymers
Chromatography, Gel
Guanylate Cyclase
Molecular Sequence Data
Mutation
Oligodeoxyribonucleotides
Sequence Deletion

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.