Article
Identification of sequences mediating guanylyl cyclase dimerization.
Biochemistry - 11 Apr 1995
Wilson E M, Chinkers M
Abstract excerpt
Deletion mutagenesis was used to identify sequences required for dimerization and enzymatic activity of the intracellular domain of the membrane guanylyl cyclase, GC-A. The intracellular domain of GC-A contains a protein kinase-like domain near its amino terminus, a guanylyl cyclase catalytic domain near its carboxyl terminus, and, between these domains, a region of unknown function predicted to form an...
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