Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular and cellular physiology of the dissociation of atrial natriuretic peptide from guanylyl cyclase a receptors.

The Journal of biological chemistry - 28 Sept 2001

Vieira M A, Gao M, Nikonova L N, Maack T

Abstract excerpt

Guanylyl cyclase subtype A (GCA) is the main receptor that mediates the effects of atrial natriuretic peptide (ANP) in the regulation of plasma volume and blood pressure. The dynamics of the dissociation of ANP from GCA were investigated in cultured Chinese hamster ovary (CHO) cells stably transfected with wild-type (WT) or mutant GCA receptors. The rate of dissociation of specifically bound (125)I-ANP-(1-28)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alanine
Share to Atrial Natriuretic Factor
Share to Binding, Competitive

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclic GMP

Share to Glycine

Share to Guanylate Cyclase

Share to Receptors, Atrial Natriuretic Factor

Share to Serine

Source

Identifiers

PMID: 11479286
DOI: 10.1074/jbc.M102208200

Genes

GCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular and cellular physiology of the dissociation of atrial natriuretic peptide from guanylyl cyclase a receptors.PMID 11479286Read ↗

Internalization and trafficking of guanylyl cyclase/natriuretic peptide receptor-A.Semantic proximity Read ↗

Identification and characterization of the phosphorylation sites of the guanylyl cyclase-linked natriuretic peptide receptors A and B.Semantic proximity Read ↗

Dominant negative mutations of the guanylyl cyclase-A receptor. Extracellular domain deletion and catalytic domain point mutations.Semantic proximity Read ↗

A constitutively "phosphorylated" guanylyl cyclase-linked atrial natriuretic peptide receptor mutant is resistant to desensitization.Semantic proximity Read ↗

Internalization and trafficking of guanylyl (guanylate) cyclase/natriuretic peptide receptor A is regulated by an acidic tyrosine-based cytoplasmic motif GDAY.Semantic proximity Read ↗

NPR-C: a component of the natriuretic peptide family with implications in human diseases.Semantic proximity Read ↗

Identification of the G protein-activating sequence of the single-transmembrane natriuretic peptide receptor C (NPR-C).Semantic proximity Read ↗

Adenine nucleotides decrease the apparent Km of endogenous natriuretic peptide receptors for GTP.Semantic proximity Read ↗

Auto-inhibition of adenylyl cyclase 9 (AC9) by an isoform-specific motif in the carboxyl-terminal region.Semantic proximity Read ↗

NK1 receptor fused to beta-arrestin displays a single-component, high-affinity molecular phenotype.Semantic proximity Read ↗

Adenylate cyclase/cAMP/protein kinase A signaling pathway inhibits endothelin type A receptor-operated Ca²⁺ entry mediated via transient receptor potential canonical 6 channels.Semantic proximity Read ↗

Role of FQQI motif in the internalization, trafficking, and signaling of guanylyl-cyclase/natriuretic peptide receptor-A in cultured murine mesangial cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.