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Article

High IL-4 production is a stable phenotype of CD8negCD45RAnegCD27neg T cells.

Cellular immunology - 1 Feb 1995

Sunder-Plassmann R, Majdic O, Knapp W, Holter W

Abstract excerpt

CD27neg T cells are found only among CD4pos-CD45ROpos T cells and represent a T cell subset functionally distinct from CD27pos T cells. We examined CD4posCD45ROpos T cells that were sorted into CD27neg and CD27pos populations for their cytokine production in response to different activation pathways. We found that CD27neg T cells are characterized by high IL-4 and low IL-2 production, regardless of whether the...

Topics

Adult
CD2 Antigens
CD28 Antigens
CD3 Complex
CD4-Positive T-Lymphocytes
CD8 Antigens
Humans
Interleukin-2
Interleukin-4
Leukocyte Common Antigens
Lymphocyte Activation
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phytohemagglutinins

T-Lymphocyte Subsets

Tetradecanoylphorbol Acetate

Tumor Necrosis Factor Receptor Superfamily, Member 7

Source

Identifiers

PMID: 7720093
DOI: 10.1016/0008-8749(95)80043-i

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7720093-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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