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Article

Regulatory function of cytomegalovirus-specific CD4+CD27-CD28- T cells.

Virology - 15 Mar 2010

Tovar-Salazar Adriana, Patterson-Bartlett Julie, Jesser Renee, Weinberg Adriana

Abstract excerpt

CMV infection is characterized by high of frequencies of CD27-CD28- T cells. Here we demonstrate that CMV-specific CD4+CD27-CD28- cells are regulatory T cells (TR). CD4+CD27-CD28- cells sorted from CMV-stimulated PBMC of CMV-seropositive donors inhibited de novo CMV-specific proliferation of autologous PBMC in a dose-dependent fashion. Compared with the entire CMV-stimulated CD4+ T-cell population, higher...

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Source

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Identifiers

PMID: 20034645
DOI: 10.1016/j.virol.2009.11.038
PMCID: PMC2823847

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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