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Article

RFLP alleles at the tyrosine hydroxylase locus: no association found to affective disorders.

Psychiatry research - 1 Jun 1990

Körner J, Fritze J, Propping P

Abstract excerpt

Affective disorders are usually referred to as being inherited multifactorially. The contribution of a gene locus in illnesses displaying multifactorial inheritance may be assessed by searching for associations of alleles to the illness. The tyrosine hydroxylase gene encodes the rate-limiting enzyme in the synthesis of catecholamines and might be a candidate for causing the manic-depressive phenotype. Therefore,...

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Source

Identifiers

PMID: 1975102
DOI: 10.1016/0165-1781(90)90032-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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RFLP alleles at the tyrosine hydroxylase locus: no association found to affective disorders.PMID 1975102Read ↗

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Association and haplotype analysis at the tyrosine hydroxylase locus in a combined German-British sample of manic depressive patients and controls.Semantic proximity Read ↗

Tyrosine hydroxylase polymorphisms and bipolar affective disorder.Semantic proximity Read ↗

Tyrosine hydroxylase gene associated with depressive symptomatology in mood disorder.Semantic proximity Read ↗

Adjacent genetic markers on chromosome 11p15.5 at or near the tyrosine hydroxylase locus that show population linkage disequilibrium with each other do not show allelic association with bipolar affective disorder.Semantic proximity Read ↗

Excess tyrosine hydroxylase restriction fragment length polymorphism homozygosity in unipolar but not bipolar patients: a preliminary report.Semantic proximity Read ↗

No evidence for an association of affective disorders with high- or low-activity allele of catechol-o-methyltransferase gene.Semantic proximity Read ↗

Tyrosine hydroxylase polymorphism and phenotypic heterogeneity in bipolar affective disorder: a multicenter association study.Semantic proximity Read ↗

Analysis of the monoamine oxidase A (MAOA) gene in bipolar affective disorder by association studies, meta-analyses, and sequencing of the promoterSemantic proximity Read ↗

Genetic association between monoamine oxidase A microsatellite and RFLP alleles and bipolar affective disorder: analysis and meta-analysis.Semantic proximity Read ↗

Genetic association between monoamine oxidase and manic-depressive illness: comparison of relative risk and haplotype relative risk data.Semantic proximity Read ↗

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