Lactate dehydrogenase-release assay: a reliable, nonradioactive technique for analysis of cytotoxic lymphocyte-mediated lytic activity against blasts from acute myelocytic leukemia.

doi:10.1007/BF01682036

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Article

Lactate dehydrogenase-release assay: a reliable, nonradioactive technique for analysis of cytotoxic lymphocyte-mediated lytic activity against blasts from acute myelocytic leukemia.

Annals of hematology - 1 Mar 1995

Weidmann E, Brieger J, Jahn B, Hoelzer D, Bergmann L, Mitrou P S

Abstract excerpt

Treatment of patients in remission of acute myelocytic leukemia using immunotherapy with interleukin 2 is a new approach to prolonging remission duration in this disease. As an important mechanism for the pathophysiology of eradication of residual myelocytic blast populations, activation of cytotoxic effector lymphocytes has frequently been discussed. However, the associated immunological research has been...

Topics

Blast Crisis
Bone Marrow Cells
CD4 Antigens
CD4-Positive T-Lymphocytes
CD8 Antigens
CD8-Positive T-Lymphocytes
Cell Line
Clinical Enzyme Tests
Clone Cells
Cytotoxicity, Immunologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Interleukin-2

L-Lactate Dehydrogenase

Leukemia, Myeloid, Acute

Lymphocyte Activation

Phenotype

Reproducibility of Results

T-Lymphocytes, Cytotoxic

Source

Open in PubMed

Identifiers

PMID: 7718644
DOI: 10.1007/BF01682036

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7718644-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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