Article
Identification of HLA-unrestricted CD8+/CD28- cytotoxic T-cell clones specific for leukemic blasts in children with acute leukemia.
Cancer research - 1 Sept 1995
Montagna D, Aricò M, Montini E, De Benedetti F, Maccario R
Abstract excerpt
We report on the identification of 57 T-cell clones (TCC) cytolytic to autologous leukemic blasts (LB) but not autologous bone marrow remission cells. LB-reactive TCC were obtained from 3 children with acute leukemia at remission; all expressed the same phenotype, CD3/TCR alpha beta/CD8+, but were heterogeneous for the expression of V beta T-cell receptor (TCR) V region chains, thus showing that these cells were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
