Article
Epidemiology, Diagnosis and Genetics of Retinoblastoma: ICMR Consensus Guidelines.
Indian journal of pediatrics - 1 Nov 2024
Singh Lata, Chinnaswamy Girish, Meel Rachna, Radhakrishnan Venkatraman, Madan Renu, Kulkarni Suyash, Sasi Archana, Kaur Tanvir, Dhaliwal R S, Bakhshi Sameer
Abstract excerpt
Retinoblastoma (RB) is the most common intraocular tumor in childhood. It is mainly caused by mutations in both alleles of the RB1 tumor suppressor gene that is found on chromosome 13 and regulates the cell cycle. Approximately 8000 children are diagnosed with RB globally each year, with an estimated 1500 cases occurring in India. The survival rate of RB has improved to more than 90% in the developed world....
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