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Article

The role of infectious disease, inbreeding and mating preferences in maintaining MHC genetic diversity: an experimental test.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Nov 1994

Potts W K, Manning C J, Wakeland E K

Abstract excerpt

In house mice, and probably most mammals, major histocompatibility complex (MHC) gene products influence both immune recognition and individual odours in an allele-specific fashion. Although it is generally assumed that some form of pathogen-driven balancing selection is responsible for the unprecedented genetic diversity of MHC genes, the MHC-based mating preferences observed in house mice are sufficient to...

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PMID: 7708831
DOI: 10.1098/rstb.1994.0154

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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