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Article

Major histocompatibility complex heterozygosity enhances reproductive success.

Molecular ecology - 1 Apr 2011

Thoss M, Ilmonen P, Musolf K, Penn D J

Abstract excerpt

We investigated how heterozygosity at the major histocompatibility complex (MHC) affects fitness in wild-derived (F2) house mice (Mus musculus musculus). To compare and control for potential confounding effects from close inbreeding and genome-wide heterozygosity, we used mice that were systematically outbred. We assessed how heterozygosity at MHC and background loci (using 15 microsatellite markers on 11...

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Identifiers

PMID: 21291500
DOI: 10.1111/j.1365-294X.2011.05009.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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