Molecular basis and PCR-DNA typing of the Fya/fyb blood group polymorphism.

doi:10.1007/BF00208965

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Article

Molecular basis and PCR-DNA typing of the Fya/fyb blood group polymorphism.

Human genetics - 1 Apr 1995

Tournamille C, Le Van Kim C, Gane P, Cartron J P, Colin Y

Abstract excerpt

The Duffy blood group antigens are carried by the erythrocyte membrane glycoprotein gpD, which has a molecular weight of 35-45 kDa and which has been recently cloned. In this report, we have determined, at the nucleic acid level, the molecular basis for the blood group Fya/Fyb polymorphism. The gpD cDNAs isolated by reverse transcription/polymerase chain reaction (RT-PCR) from Fy(a+b-) and Fy(a-b+) donors...

Topics

Alleles
Animals
Base Sequence
Blood Grouping and Crossmatching
Blood Proteins
Cell Line
DNA
DNA Primers
Duffy Blood-Group System
Erythrocyte Membrane
Gene Expression
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macaca

Membrane Glycoproteins

Molecular Biology

Molecular Sequence Data

Polymerase Chain Reaction

Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 7705836
DOI: 10.1007/BF00208965

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7705836-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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