Article
Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface.
Genetics - 1 Jan 1995
Bejsovec A, Wieschaus E
Abstract excerpt
The Drosophila segment polarity gene wingless encodes an intercellular signaling molecule that transmits positional information during development of the embryonic epidermis. We have explored the mechanism of wg signal transduction by perturbing cellular processes genetically and by performing structure/function analysis of the Wg protein. We present evidence that Wingless protein may transduce signal at the cell...
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