Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface.

doi:10.1093/genetics/139.1.309

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Article

Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface.

Genetics - 1 Jan 1995

Bejsovec A, Wieschaus E

Abstract excerpt

The Drosophila segment polarity gene wingless encodes an intercellular signaling molecule that transmits positional information during development of the embryonic epidermis. We have explored the mechanism of wg signal transduction by perturbing cellular processes genetically and by performing structure/function analysis of the Wg protein. We present evidence that Wingless protein may transduce signal at the cell...

Topics

Amino Acid Sequence
Animals
Armadillo Domain Proteins
Base Sequence
Biological Transport
Drosophila
Drosophila Proteins
Dynamins
Epidermis
Fluorescent Antibody Technique
GTP Phosphohydrolases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression

Genes, Insect

In Situ Hybridization

Ligands

Molecular Sequence Data

Mutation

Proteins

Source

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Identifiers

PMID: 7705631
DOI: 10.1093/genetics/139.1.309
PMCID: PMC1206327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7705631-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface.PMID 7705631Read ↗

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