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Computer image analysis of comparative genomic hybridization

1 Jan 1995

Abstract excerpt

We describe and evaluate the image-processing and analysis techniques we have developed for the quantitative analysis of comparative genomic hybridization (CGH; Science 258:818, 1992). In a typical CGH application, two genomic DNA samples are simultaneously hybridized to metaphase chromosomes and detected with different fluorochromes. The primary data in CGH are contained in the intensity ratios of the...

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PMID: 7705181
DOI: 10.1002/cyto.990190104

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Source receipt: pubmed, retrieved 7 Sept 2026.

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