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Article

Comparative genomic hybridization.

Annual review of genomics and human genetics - 1 Jan 2005

Pinkel Daniel, Albertson Donna G

Abstract excerpt

Altering DNA copy number is one of the many ways that gene expression and function may be modified. Some variations are found among normal individuals ( 14, 35, 103 ), others occur in the course of normal processes in some species ( 33 ), and still others participate in causing various disease states. For example, many defects in human development are due to gains and losses of chromosomes and chromosomal...

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Identifiers

PMID: 16124865
DOI: 10.1146/annurev.genom.6.080604.162140

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