Article
In Saccharomyces cerevisiae deletion of phosphoglucose isomerase can be suppressed by increased activities of enzymes of the hexose monophosphate pathway.
Microbiology (Reading, England) - 1 Feb 1995
Dickinson J R, Sobanski M A, Hewlins M J
Abstract excerpt
Saccharomyces cerevisiae mutants defective in the structural gene PGI1 lack phosphoglucose isomerase and hence cannot grow on glucose. Spontaneous mutants were isolated by selecting for the regained ability to grow on YEPD (yeast extract/peptone/glucose). Three complementation groups called spg29...
Topics
- Enzymes
- Gene Deletion
- Genes, Fungal
- Genetic Complementation Test
- Glucose
- Glucose-6-Phosphate Isomerase
- Glycolysis
- Magnetic Resonance Spectroscopy
- Mutation
- Pentose Phosphate Pathway
- Saccharomyces cerevisiae
- Suppression, Genetic