Article
Control of glucose influx into glycolysis and pleiotropic effects studied in different isogenic sets of Saccharomyces cerevisiae mutants in trehalose biosynthesis.
Current genetics - 1 Jan 1995
Neves M J, Hohmann S, Bell W, Dumortier F, Luyten K, Ramos J, Cobbaert P, de Koning W, Kaneva Z, Thevelein J M
Abstract excerpt
The GGS1/TPS1 gene of the yeast Saccharomyces cerevisiae encodes the trehalose-6-phosphate synthase subunit of the trehalose synthase complex. Mutants defective in GGS1/TPS1 have been isolated repeatedly and they showed variable pleiotropic phenotypes, in particular with respect to trehalose content, ability to grow on fermentable sugars, glucose-induced signaling and sporulation capacity. We have introduced the...
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