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Article

Evolution of a Saccharomyces cerevisiae metabolic pathway in Escherichia coli.

Metabolic engineering - 1 Mar 2007

Meynial Salles Isabelle, Forchhammer Nynne, Croux Christian, Girbal Laurence, Soucaille Philippe

Abstract excerpt

The Saccharomyces cerevisiae glycerol pathway (GPD1 and GPP2) was evolved in vivo in Escherichia coli. The central metabolism of E. coli was engineered to link glucose consumption and glycerol production. The engineered strain was evolved in a chemostat culture and a high glycerol producer was rapidly obtained. The evolution of the strain was associated to a deletion between GPD1 and GPP2, resulting in the...

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Source

Identifiers

PMID: 17113805
DOI: 10.1016/j.ymben.2006.09.002

Genes

GPD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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