Article
The role of the NAD-dependent glutamate dehydrogenase in restoring growth on glucose of a Saccharomyces cerevisiae phosphoglucose isomerase mutant.
European journal of biochemistry - 1 Oct 1993
Boles E, Lehnert W, Zimmermann F K
Abstract excerpt
Phosphoglucose isomerase pgi1-deletion mutants of Saccharomyces cerevisiae cannot grow on glucose as the sole carbon source and are even inhibited by glucose. These growth defects could be suppressed by an over-expression on a multi-copy plasmid of the structural gene GDH2 coding for the NAD-depe...
Topics
- Amino Acid Sequence
- Base Sequence
- Gene Deletion
- Gene Expression
- Glucose
- Glucose-6-Phosphate Isomerase
- Glutamate Dehydrogenase
- Glutamates
- Glutamic Acid
- Ketoglutaric Acids
- Models, Genetic
- Molecular Sequence Data
- Mutation
- NAD
- NADP
- Plasmids
- Restriction Mapping
- Saccharomyces cerevisiae