Article
HLA-DRB1 alleles and Jk(a) immunization.
Transfusion - 1 Jun 2005
Reviron Denis, Dettori Isabelle, Ferrera Virginie, Legrand Dominique, Touinssi Mhammed, Mercier Pierre, de Micco Philippe, Chiaroni Jacques
Abstract excerpt
BACKGROUND: In transfusion medicine, anti-Jk(a) has been implicated in hemolytic transfusion reactions. Development of anti-Jk(a) after transfusion does not always occur after Jk(a-) patients receive at least 1 unit of Jk(a+) blood unit. This study was designed to identify HLA-DRB1 alleles associated with predisposition to Jk(a) immunization after blood transfusion or pregnancy. STUDY DESIGN AND METHODS:...
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