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[Analysis of the distribution frequencies of HLA-A and HLA-B alleles in patients with immune-mediated Platelet transfusion refractoriness].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Dec 2025

Liu Ying, Xie Zuonian, Liu Heqiong, Xu Xianguo, Zhang Wei, Zhu Faming

Abstract excerpt

OBJECTIVE: To analyze the distribution frequency and characteristics of HLA-A and HLA-B loci in patients with immune-mediated Platelet transfusion refractoriness (iPTR) in order to provide data support for investigating HLA gene matching strategies for platelet transfusion and improving transfusion efficacy. METHODS: A total of 532 iPTR patients who applied for gene matched platelet at the Blood Center of...

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PMID: 41811037
DOI: 10.3760/cma.j.cn511374-20250515-00298

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