Article
Dual T cell receptor beta chain expression on human T lymphocytes.
The Journal of experimental medicine - 1 Apr 1995
Davodeau F, Peyrat M A, Romagné F, Necker A, Hallet M M, Vié H, Bonneville M
Abstract excerpt
Allelic exclusion of lymphocyte antigen receptor chains has been hypothesized as a mechanism developed by the immune system to ensure efficient lymphocyte repertoire selection and tight control of lymphocyte specificity. It was effectively shown to be operative for both the immunoglobulin (Ig) and the T cell receptor (TCR) beta chain genes. Our present observations suggest that close to 1% of human T lymphocytes...
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