Article
Association of primary biliary cirrhosis with human leukocyte antigen DPB1*0501 in Japanese patients.
Hepatology (Baltimore, Md.) - 1 Jul 1993
Seki T, Kiyosawa K, Ota M, Furuta S, Fukushima H, Tanaka E, Yoshizawa K, Kumagai T, Mizuki N, Ando A
Abstract excerpt
To investigate the relationship between distribution of human leukocyte antigen alleles and susceptibility to primary biliary cirrhosis among Japanese, we performed serological typing and human leukocyte antigen DP genotyping in 47 Japanese patients with primary biliary cirrhosis. Serologically, the frequency of human leukocyte antigen DQ3 was significantly higher in the patients than in healthy controls, whereas...
Topics
- Adult
- Aged
- Amino Acid Sequence
- Female
- Genotype
- HLA-DP Antigens
- HLA-DP beta-Chains
- HLA-DQ Antigens
- HLA-DR Antigens
- Humans
- Japan
- Liver Cirrhosis, Biliary