Article
Immortalization of epithelial cells.
The American journal of physiology - 1 Jan 1996
Hopfer U, Jacobberger J W, Gruenert D C, Eckert R L, Jat P S, Whitsett J A
Abstract excerpt
The methodologies for isolating cell lines have become very powerful, particularly in terms of retaining differentiated features of the parent cells. Cell lines can be developed from primary or early passage cells as well as from transgenic animals that carry an immortalizing gene. Cell lines from epithelia have been selected for their polar orientation, tight junction formation, and expression of differentiated...
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