Article
Changes in orexin-A and neuropeptide y expression in the hypothalamus of obese and lean Zucker Diabetic Fatty rats.
The Journal of veterinary medical science - 1 Jul 2005
Park Eun Sung, Seong Je Kyung, Yi Seong Joon, Kim Jin Sang, Lee Heungshik S, Lee In Se, Yoon Yeo Sung
Abstract excerpt
This study was carried out to investigate the changes of orexin-A (OXA) and neuropeptide Y (NPY) expression in the hypothalamus of the obese and lean Zucker Diabetic Fatty (ZDF) rats which have a missense mutation in the leptin receptor gene. The mean body weights (MBW) between the obese and lean ZDF rats were significantly different at 28 and 70 postnatal days. However, at 14 postnatal day, there was no...
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