Article
Malignant lymphoma originating from the earliest T-lineage precursor cell.
American journal of hematology - 1 Aug 1993
Hashimoto Y, Yasukawa M, Takada K, Hato T, Fujita S
Abstract excerpt
The earliest T-lineage precursor cells with a CD3-CD4+CD8- phenotype and germline-state T-cell receptor (TCR) genes have recently been identified in the murine thymus. We report a case of malignant lymphoma that was considered to originate from the human counterpart of this newly defined murine T-cell population. The surface phenotype of the lymphoma cells was CD2+CD3-CD4+CD8-CD25-CD34-CD44+HLA-DR+. TCR-beta,...
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