Article
Malignant lymphoma originating from the earliest T-lineage precursor cell.
American journal of hematology - 1 Aug 1993
Hashimoto Y, Yasukawa M, Takada K, Hato T, Fujita S
Abstract excerpt
The earliest T-lineage precursor cells with a CD3-CD4+CD8- phenotype and germline-state T-cell receptor (TCR) genes have recently been identified in the murine thymus. We report a case of malignant lymphoma that was considered to originate from the human counterpart of this newly defined murine T...
Topics
- Adolescent
- Antigens, CD
- Antigens, CD34
- CD3 Complex
- CD4 Antigens
- CD8 Antigens
- Cell Transformation, Neoplastic
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Gene Rearrangement, delta-Chain T-Cell Antigen Receptor
- Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor
- HLA-DR Antigens
- Humans
- Immunoglobulin Heavy Chains
- Immunoglobulin Light Chains
- Lymphoma
- Male
- Phenotype
- Receptors, Antigen, T-Cell, alpha-beta