Article
Stability governs the apparent expression of "particulate" hepatitis B e antigen by mutant hepatitis B virus core particles.
Virology - 1 Sept 1993
Seifer M, Standring D N
Abstract excerpt
The p21.5 capsid or core protein of hepatitis B virus carries two distinct classes of epitopes. Core (HBc) epitopes are found exclusively on the surface of the 28-nm viral icosahedral capsids or core particles, while HBe epitopes are normally expressed only by subparticulate forms of the core protein. Recent studies have suggested that a "particulate" form of HBe is expressed on the surface of capsid particles...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Capsid
- Cysteine
- Enzyme-Linked Immunosorbent Assay
- Epitopes
- Escherichia coli
- Freezing
- Hepatitis B Core Antigens
- Hepatitis B e Antigens
