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Article

Modulation of the immunogenicity of virus-like particles composed of mutant hepatitis B virus envelope subunits.

Antiviral research - 1 Feb 2012

Cheong Wan-Shoo, Hyakumura Michiko, Yuen Lilly, Warner Nadia, Locarnini Stephen, Netter Hans J

Abstract excerpt

Virus-like particles (VLPs) are non-infectious subviral protein complexes, which possess structural features identical or closely related to infectious virions. They are utilized as delivery tools for immunologically relevant antigenic sequences. In order to investigate whether mutant subunits can modulate the VLP immunogenicity, comparative immunization studies with wild-type and non-native VLPs were performed....

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Identifiers

PMID: 22138713
DOI: 10.1016/j.antiviral.2011.11.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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