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Article

Hepatitis B Virus Core Particles as Epitope Carriers

1 Jan 1995

Abstract excerpt

HBV core (HBc) particle is one of the most intensively studied particulate carriers for the insertion of foreign peptide sequences. Recombinant HBc protein expressed from the cloned gene undergoes the correct folding in a large variety of bacterial, yeast, insect and mammalian cells. Unique assembly properties and shape of 30/34-nm HBc particles allow substantial insertions into their primary structure without...

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PMID: 8666525
DOI: 10.1159/000150415

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