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Control of Murine Cytomegalovirus Infection by γδ T Cells

6 Feb 2015

Abstract excerpt

Infections with cytomegalovirus (CMV) can cause severe disease in immunosuppressed patients and infected newborns. Innate as well as cellular and humoral adaptive immune effector functions contribute to the control of CMV in immunocompetent individuals. None of the innate or adaptive immune functions are essential for virus control, however. Expansion of γδ T cells has been observed during human CMV (HCMV)...

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PMID: 25658831
DOI: 10.1371/journal.ppat.1004481

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