Article
Murine cytomegalovirus replication in salivary glands is controlled by both perforin and granzymes during acute infection.
European journal of immunology - 1 May 2000
Riera L, Gariglio M, Valente G, Müllbacher A, Museteanu C, Landolfo S, Simon M M
Abstract excerpt
The course of mouse cytomegalovirus (MCMV) infection was compared between wild-type and mutant C57BL / 6 (B6) mice deficient in either RAG-2, perforin, granzyme A, granzyme B or combinations thereof at two time points post infection (p. i.). At day 15 p. i., virus titers were similarly elevated in salivary glands of all mutant, but not wild-type B6 mice and undetectable in lung and spleen tissues of any of the...
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