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Article

Interferon-gamma and tumor necrosis factor-alpha enhance p60src expression in human macrophages and myelomonocytic cell lines.

FEBS letters - 2 Aug 1993

Sorio C, Melotti P, Dusi S, Berton G

Abstract excerpt

We investigated modulation of p60src expression in human mononuclear phagocytes. By analysis of [35S]methionine-labelled cells we found that synthesis of p60src is higher in human monocytes compared to macrophages derived from in vitro cultivation of monocytes. Western blot analysis showed that expression of p60src in monocyte-derived macrophages can be enhanced if monocytes are differentiated into macrophages in...

Topics

Cell Differentiation
Cells, Cultured
Humans
Interferon-gamma
Leukemia, Myelomonocytic, Acute
Macrophages
Phenotype
Phosphorylation
Proto-Oncogene Proteins pp60(c-src)
Tumor Cells, Cultured
Tumor Necrosis Factor-alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7688696
DOI: 10.1016/0014-5793(93)81012-o

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7688696-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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