In vivo administration of stem cell factor to mice increases the absolute number of pluripotent hematopoietic stem cells.

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Article

In vivo administration of stem cell factor to mice increases the absolute number of pluripotent hematopoietic stem cells.

Blood - 15 Jul 1993

Bodine D M, Seidel N E, Zsebo K M, Orlic D

Abstract excerpt

We have examined the effects of administration of stem cell-factor (SCF) on the number and distribution of pluripotent hematopoietic stem cells (PHSC) in normal mice. Using the competitive repopulation assay we found that in vivo administration of SCF increases the absolute number of PHSC per mou...

Topics

Animals
Bone Marrow
Bone Marrow Cells
Cell Count
DNA
Drug Resistance
Erythroid Precursor Cells
Fluorouracil
Granulocytes
Hematopoietic Cell Growth Factors
Hematopoietic Stem Cells
Lymphocytes
Mice
Mice, Inbred C57BL
Phenotype
Polyethylene Glycols
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-kit

Source

Open in PubMed

Identifiers

PMID: 7687160

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7687160-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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