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Article

Genetic control of the frequency of hematopoietic stem cells in mice: mapping of a candidate locus to chromosome 1.

The Journal of experimental medicine - 1 Mar 1996

Müller-Sieburg C E, Riblet R

Abstract excerpt

The genetic elements that govern the differentiation and proliferation of hematopoietic stem cells remain to be defined. We describe here marked strain-specific differences in the frequency of long-term culture-initiating cells (LTC-IC) in the bone marrow of different strains of mice. Mice of C57Bl/6 background showed the lowest levels of stem cells in marrow, averaging 2.4 +/- .06 LTC-IC/10(5) cells, BALB/c is...

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Identifiers

PMID: 8642256
DOI: 10.1084/jem.183.3.1141
PMCID: PMC2192322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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