Article
CFTR expression and organ damage in cystic fibrosis.
Annals of internal medicine - 15 Aug 1995
Tizzano E F, Buchwald M
Abstract excerpt
The cloning of the defective gene in cystic fibrosis (CFTR) is the most important step to date toward understanding the pathogenesis of the disease and developing novel therapeutic strategies. Although many studies have provided insights into the molecular defects and knowledge of the expression...
Topics
- Chloride Channels
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Gene Expression Regulation
- Genotype
- Humans
- Membrane Proteins
- Mutation