Article
Evidence for a weak adaptive response to alkylation damage in Vibrio cholerae.
Mutation research - 1 Jan 1995
Bhasin N, Ghosh A
Abstract excerpt
Wild-type Vibrio cholerae cells, when adapted by a stepwise treatment with sub-lethal concentrations of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), acquired resistance to killing and mutagenesis by subsequent challenges with higher concentrations of MNNG. This was also seen in the rec isogenic strain indicating that the observed phenomenon was not due to the induction of SOS functions. Further, the adapted cells...
Topics
- Adaptation, Physiological
- Bacterial Proteins
- Enzyme Induction
- Escherichia coli
- Escherichia coli Proteins
- Methylnitronitrosoguanidine
- Methyltransferases
- Mutation
- O(6)-Methylguanine-DNA Methyltransferase
- Transcription Factors
- Vibrio cholerae