Retinoid status controls the appearance of reserve cells and keratin expression in mouse cervical epithelium.

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Article

Retinoid status controls the appearance of reserve cells and keratin expression in mouse cervical epithelium.

Cancer research - 15 May 1993

Darwiche N, Celli G, Sly L, Lancillotti F, De Luca L M

Abstract excerpt

We describe an animal model to induce the histogenesis of squamous metaplasia of the cervical columnar epithelium, a condition usually preceding cervical neoplasia. This model is based on dietary retinoid depletion in female mice. Control sibling mice fed the same diet but with all-trans-retinoic...

Topics

Animals
Carcinoma, Squamous Cell
Cervix Uteri
Diet
Disease Models, Animal
Epithelium
Female
Immunohistochemistry
In Situ Hybridization
Keratins
Metaplasia
Mice
Mice, Inbred BALB C
Mice, Nude
Phenotype
Precancerous Conditions
RNA, Messenger
Retinoids

Source

Open in PubMed

Identifiers

PMID: 7683571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7683571-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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