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Article

Herpes simplex virus particles are unable to traverse the secretory pathway in the mouse L-cell mutant gro29.

Journal of virology - 1 Dec 1990

Banfield B W, Tufaro F

Abstract excerpt

The mouse L-cell mutant gro29 was selected for its ability to survive infection by herpes simplex virus type 1 (HSV-1) and is defective in the propagation of HSV-1 and vesicular stomatitis virus (F. Tufaro, M. D. Snider, and S. L. McKnight, J. Cell Biol. 105:647-657, 1987). In this report, we show that gro29 cells harbor a lesion that inhibits the egress of HSV-1 virions during infection. We also found that HSV-1...

Topics

Animals
Blotting, Western
Cell Transformation, Viral
Fluorescent Antibody Technique
Kinetics
L Cells
Mice
Microsomes
Monensin
Mutation
Simplexvirus
Viral Envelope Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Virion

Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 2173764
DOI: 10.1128/JVI.64.12.5716-5729.1990
PMCID: PMC248713

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2173764-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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